Accommodation / Ten (10) to Inspire / Wildlife Encounters

Big 5 Malaria Free Game Reserves in South Africa

Updated Tuesday, 14 March 2023

For those who don’t want to worry about taking anti-malaria pills, malaria free game reserves do exist in South Africa.

Plenty of them.

We understand that game viewing is your priority, not having to think about taking pills that don’t necessarily taste all that good.

And whilst a Big 5 game viewing holiday in the Kruger National Park is top of many first time visitors’ lists, it comes with the threat of moderate-risk malaria and the need to take prophylactics between September and May.

You should know that things in Africa have hugely improved with regards to malaria control, even if deaths from the disease have remained largely unchanged over the last couple of years.

Malaria Free Game Reserves - This is GORAH

Interestingly the best way to prevent malaria, with anti-malarials, is still not a consistent measure in those countries where malaria, particularly amongst children, is prevalent during the rainy season when mosquitoes are rife.

South Africa was named by the WHO as one of five African countries most likely to eliminate malaria by 2020.

The good news for all visitors to the country is that malaria free game reserves in South Africa are plenty and there is a huge choice available to you.

Malaria Risk areas in South Africa: the country’s three north easternmost provinces – KwaZulu-Natal, Mpumalanga and Limpopo (and only in their outermost regions)

Malaria free areas in South Africa: Eastern Cape, Northwest & Madikwe, Waterberg, and Northern Cape

Malaria Free Game Reserves - This is KARIEGA

We’ve put together a list of top Big Five malaria free game reserves in South Africa for you…


Askari Game Lodge

Experience the African veld and wildlife just over an hour from Johannesburg with the Magaliesberg as your backdrop. The main lodge overlooks the elephant dam, the spa will help you unwind and the private collections of ox wagons intrigue.

At Askari Game Lodge

Tau Game Lodge

If the sound of lions tongues lapping at the river’s edge just outside your window is enough to delight you, then Tau will more than reward your expectations of Big 5 and the sense of getting away from it all in the African bush.

Malaria Free Game Reserves Tau Game Lodge

Impodimo Game Lodge

Impodimo is another option for you at Madikwe Game Reserve (there are several) offering eight glass fronted chalets along the edge of a spring with incredible views, meals and tracking of game on foot.

Malaria Free Game Reserves Impodimo Game Lodge

Tambuti Lodge

Close to Sun City, Tambuti Lodge lies in the Black Rhino Game Reserve of the well known Big 5 Pilanesberg National Park with game drives, walks and bird spotting. Modern, fun and close to Johannesburg.

Tambuti Lodge

Shepherd’s Tree Game Lodge

Shepherd’s Tree is a more upmarket offering on the south-western side of the Pilanesberg National Park, adjacent to the Wilderness Area with great walking trails and setting. There’s also a gourmet restaurant and outdoor boma.

Shepherd’s Tree Game Lodge Malaria Free Game reserves

Black Rhino Lodge

Our third offering in the Pilanesberg (and within reason given how close it brings Big Five viewing to South Africa’s major metropole), Black Rhino Lodge overlooks a waterhole often busy with buffalo and elephants.

Black Rhino Lodge

Need more options? See more North West Province Game Lodges


Marataba Safari Lodge

You’ll relish the natural environment and its rich red mountain magnificence alone (the mountain views at this safari lodge are exceptional), but throw in a chance to see the Big Five on foot and it becomes unmissable.

Marataba Safari Lodge

Entabeni Safari Conservancy

22 000 hectares of ravines, dense bushveld and forested hills are yours for the duration of your stay in the Waterberg Biosphere. Dubbed ‘the place of the mountain’ Entabeni offers five different lodges.

Malaria Free Game Reserves - Entabeni Safari Conservancy

Phumelelo Lodge

Phumelelo lies in the greater Mabalingwe Nature Reserve (you need to reserve to visit the lion enclosure) with access to the Big Five, offering luxury accommodation in just four African themed chalets.

Phumelelo Lodge

Makweti Safari Lodge

You’ll find Makweti in the Welgevonden Private Game Reserve (there are no fences here and animals can wander freely through the lodge) surrounded by pristine bushveld. The lodge overlooks a waterhole from a viewing deck.

Makweti Safari Lodge

Clifftop Exclusive Safari Lodge

One of our most popular Waterberg lodges, this rather unique bushveld retreat lies right up on a clifftop in the Welgevonden Private Game Reserve, offering eight suites each with its own deck and plunge pool.

At Clifftop Exclusive Safari Lodge

Nedile Lodge

Welgevonden Game Reserve has one of the biggest collections of white rhino in the country, and these carefully positioned suites in amongst rocky outcrops, give you incredible views out across the Waterberg Mountains.

Malaria FREE Game Reserve Nedile Lodge

Sediba Game Lodge

Sediba is not strictly Big Five game viewing, but we’ve included it here anyway because we’re sure you’ll agree that their two lodges are pretty awesome when it comes to views and bush experience.

Sediba Game Lodge MALARIA FRE Game Reserves

Need more options? See all Limpopo Game Lodges


River Lodge

Oh wow, at Kariega’s River Lodge, ten thatched suites line the banks of the Bushman’s River with access to daily safari drives, river cruises and walking trails. Kariega uniquely connects the Big Five game to the sea.

Malarai FREE Kariega's River Lodge

Gorah Elephant Camp

This gorgeously colonial-style game lodge in Addo Elephant National Park, Gorah provides 11 tented luxury suites with views out over the savannah plains. The main house at Gorah is a national monument.

Gorah Elephant Camp

The Bush Lodge

Amakhala Reserve’s Bush Lodge might be only 45 minutes’ from Port Elizabeth, but the rustic luxury tented suites and viewing decks soon work their magic and you forget that city life exists outside of the bushveld.

The Bush Lodge

Settlers Drift Lodge

Settler’s Drift lies in a remote and untouched part of the Kariega wilderness, offering nine tented safari suites with decks overlooking the Bushman’s River. Settler’s Drift Lodge is exceedingly beautiful, modern and spacious.

Settlers Drift Lodge

Quatermains Camp

In the style of a classic 1920’s expedition camp (but without any of the stress or toil this time in the bush must have brought settlers), Quatermains is pure ‘adventure’ from its 1900’s style safari tents and military campaign furnishings to its relaxed central boma with an open fire.

Quatermain's Camp

Hillsnek Safaris Game Lodge

Another Amakhala Game Reserve option, Hillsnek lies in amongst the hills above the Bushman’s River with incredible views and safari tents on wooden decks. It’s an ‘exclusive-use’ lodge with its own host, chef, ranger and landrover at your disposal.

HillsNek Safaris

Ukhozi Lodge

Quirky decor and a superb location make this Kariega Game Reserve option well worth it. Ten luxury suites and private plunge pools overlook the valley beyond making this unique malaria fre game reserve an excellent choice.

Kariega Ukhozi Lodge

Please Note: even though malaria is considered a killer disease the mortality figures reflect Africa’s inadequate health care rather than the prevalence of the disease. Most tourists who get malaria recover completely because of access to doctors, medicine, clean water and food. If you are at all worried about malaria you should consult your doctor and possibly take prophylactics.

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